| Physiological and psychological symptoms and predictors in early nicotine withdrawal. | |
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MedLine Citation:
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PMID: 18294681 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study assessed the structure and intensity of the nicotine withdrawal syndrome in 30 (22 male, 8 female) heavy smokers across three experimental conditions: smoking, brief abstinence (3.5 h), and extended abstinence (18 h). Physiological variables (heart rate and blood pressure) and psychological variables (anxious and depressed mood) were examined in terms of symptom validity and as predictors of nicotine withdrawal intensity. As length of abstinence increased, heart rate and blood pressure decreased, and anxious and depressed mood increased. Only anxious and depressed mood were significant individual predictors of withdrawal intensity. The symptom structure of withdrawal did not change over time as abstinence levels increased; each symptom's contribution to nicotine withdrawal intensity remained stable throughout the first 18 h of abstinence. |
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Authors:
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Holly E R Morrell; Lee M Cohen; Mustafa al'Absi |
Publication Detail:
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Type: Journal Article Date: 2008-02-21 |
Journal Detail:
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Title: Pharmacology, biochemistry, and behavior Volume: 89 ISSN: 0091-3057 ISO Abbreviation: Pharmacol. Biochem. Behav. Publication Date: 2008 May |
Date Detail:
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Created Date: 2008-03-21 Completed Date: 2008-05-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0367050 Medline TA: Pharmacol Biochem Behav Country: United States |
Other Details:
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Languages: eng Pagination: 272-8 Citation Subset: IM |
Affiliation:
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University of California, San Francisco, CA, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anxiety / etiology Blood Pressure Depression / etiology Female Heart Rate Humans Linear Models Male Nicotine / adverse effects* Substance Withdrawal Syndrome / physiopathology*, psychology* Tobacco Use Disorder / physiopathology*, psychology* |
| Chemical | |
Reg. No./Substance:
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54-11-5/Nicotine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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