| Physiological predictors of maximum treadmill walking performance in patients with intermittent claudication. | |
| | |
MedLine Citation:
|
PMID: 19214940 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The purpose of this investigation was to identify physiological predictors of maximum treadmill walking performance (MWD) in patients with intermittent claudication. Forty-five claudicants performed a graded treadmill test to determine MWD, peak oxygen uptake, and gas exchange threshold. Calf muscle oxygenation (StO (2)) at 1 min and time to minimum StO (2) were also measured using near-infrared spectroscopy. On other occasions, peak calf blood flow, resting ankle-brachial index, and pulmonary oxygen uptake kinetics during steady-state walking were assessed. A forward stepwise multiple regression analysis was performed to determine predictors of MWD. A regression model comprising time to minimum StO (2), peak oxygen uptake, and StO (2) at 1 min explained 64% of the variation in MWD. The results suggest that cardiopulmonary fitness and the ability to match oxygen delivery to metabolic demand are important determinants of walking performance in claudicants, and that certain near-infrared spectroscopy variables might be useful in studies that evaluate the mechanisms of clinical improvement with different treatment interventions. |
| | |
Authors:
|
G A Tew; S Nawaz; M Blagojevic; I Zwierska; J M Saxton |
Publication Detail:
|
Type: Journal Article Date: 2009-02-12 |
Journal Detail:
|
Title: International journal of sports medicine Volume: 30 ISSN: 1439-3964 ISO Abbreviation: Int J Sports Med Publication Date: 2009 Jun |
Date Detail:
|
Created Date: 2009-05-26 Completed Date: 2009-08-11 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8008349 Medline TA: Int J Sports Med Country: Germany |
Other Details:
|
Languages: eng Pagination: 467-72 Citation Subset: IM |
Affiliation:
|
Centre for Sport and Exercise Science, Sheffield Hallam University, United Kingdom. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Ankle Brachial Index Exercise Test / methods Exercise Tolerance Humans Intermittent Claudication / physiopathology* Leg / blood supply Male Middle Aged Oxygen Consumption* Pulmonary Gas Exchange Regression Analysis Spectroscopy, Near-Infrared / methods Walking* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Analysis of high intensity activity in Premier League soccer.
Next Document: Improvement of insulin sensitivity by a novel drug, BGP-15, in insulin-resistant patients: a proof o...