| Physiological influence of basic perturbations assessed by non-invasive optical techniques in humans. | |
| | |
MedLine Citation:
|
PMID: 22111558 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
New non-invasive techniques enabling frequent or continuous assessments of various pathophysiological conditions might be used to improve in-hospital outcome by enabling earlier and more reliable bedside detection of medical deterioration. In this preclinical study, three modern non-invasive optical techniques, laser Doppler imaging (LDI), near-infrared spectroscopy (NIRS), and tissue viability imaging (TVI), were all evaluated with respect to the influence of basic physiological perturbations (including local changes in arm positioning, skin temperature, and regional blood flow conditions) on quasi simultaneously obtained values of skin perfusion, muscle tissue oxygenation (StO(2)), and skin blood volume, recorded in eighteen healthy volunteers. Skin perfusion measured by LDI responded prominently to changes in positioning of the arm, whereas muscle StO(2) measured by NIRS did not change significantly. Total haemoglobin count (HbT) measured by NIRS and blood volume estimated by TVI both increased significantly on lowering of the limb. On local cooling, the perfusion and blood volume were both found to increase considerably, while StO(2) and HbT did not change. Local heating induced a more than 10-fold increase in skin perfusion and a small increase in blood volume. On progressive venoarterial occlusion, the perfusion, StO(2), HbT, and blood volume values decreased, after transient increases in HbT and blood volume before full arterial occlusion occurred, and all values approached the baseline level on release of the occlusion with a slight overshoot of the StO(2). The results obtained have potential bearing on future utilization of these non-invasive techniques in the management of severely injured and (or) critically ill patients. |
| | |
Authors:
|
Emilie Krite Svanberg; Per Wollmer; Stefan Andersson-Engels; Jonas Akeson |
Related Documents
:
|
7596558 - Tolerance of intravitreous interleukin-1 beta in the treatment of experimental vitreous... 7744088 - Beneficial effect of nitroglycerin on arterial rethrombosis after thrombolysis. results... 7616508 - Effect of exogenous oestrogen on blood flow and quantitative histology of the corpora l... 18040678 - The blood supply of early, late, and nonossifying cartilage: preliminary gray-scale and... 10517818 - Specificity of synergistic coronary flow enhancement by adenosine and pulsatile perfusi... 9385758 - Cerebral blood flow in chronic posttraumatic headache. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-11-23 |
Journal Detail:
|
Title: Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme Volume: - ISSN: 1715-5312 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101264333 Medline TA: Appl Physiol Nutr Metab Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
a Department of Anaesthesiology and Intensive Care Medicine, Lund University, Skåne University Hospital, entrance 42, 3rd floor, SE - 205 02 Malmö, Sweden. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The Amsterdam Executive Function Inventory (AEFI): Psychometric properties and demographically corre...
Next Document: The Crystal Chemistry of Ca(10-y)(SiO(4))(3)(SO(4))(3)Cl(2-x-2y)F(x) Ellestadite.