Document Detail

Physiological importance of omega-3/omega-6 polyunsaturated fatty acids in man. An overview of still unresolved and controversial questions.
MedLine Citation:
PMID:  2001722     Owner:  NLM     Status:  MEDLINE    
The 'essentiality' of (omega-6) and (omega-3) fatty acids in mammals is well known. Nevertheless, some important points remain unclear concerning their implication in physiology. After a short discussion about the definition of essential fatty acids deficiency, this brief overview deals with some of these points, pointing out some of the unresolved questions. Different subjects are approached concerning the (omega-6) and (omega-3) fatty acids metabolism: desaturases, eicosanoids, production, as well as some of their metabolic effects on cell membranes, intestinal function, glucose and lipid metabolism, haemorheology.
G Debry; X Pelletier
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Experientia     Volume:  47     ISSN:  0014-4754     ISO Abbreviation:  Experientia     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-04-17     Completed Date:  1991-04-17     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0376547     Medline TA:  Experientia     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  172-8     Citation Subset:  IM    
Département de Nutrition et des Maladies Métaboliques, Université de Nancy I, France.
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MeSH Terms
Blood Flow Velocity
Cell Membrane / physiology
Eicosanoids / physiology
Endoplasmic Reticulum / physiology
Fatty Acid Desaturases / physiology
Fatty Acids, Essential / deficiency,  physiology*
Fatty Acids, Omega-3 / physiology
Fatty Acids, Omega-6
Fatty Acids, Unsaturated / physiology*
Glucose / metabolism
Hormones / physiology
Intestines / physiology
Lipid Metabolism
Reg. No./Substance:
0/Eicosanoids; 0/Fatty Acids, Essential; 0/Fatty Acids, Omega-3; 0/Fatty Acids, Omega-6; 0/Fatty Acids, Unsaturated; 0/Hormones; 50-99-7/Glucose; EC 1.14.19.-/Fatty Acid Desaturases

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