Document Detail

Physiological and functional impact of an unsupervised but supported exercise programme for claudicants.
MedLine Citation:
PMID:  18547828     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To evaluate an unsupervised home-based exercise programme for physiological, functional, and quality of life impact in patients with symptomatic peripheral arterial disease. DESIGN: Prospective cohort with exercise intervention. MATERIALS: Human performance laboratory with non-invasive haemodynamic assessment facilities. METHODS: Forty-seven patients with symptomatic peripheral arterial disease (mean age 67.6+/-7 years, 33 males) participated in an unsupervised home-based exercise programme. Heart rate (HR), ankle brachial blood pressure index (ABPI), leg blood flow (BF), and blood lactate were measured before and after a graded treadmill walk at baseline and after the 12-week exercise programme. Maximum walking distance (MWD) during the treadmill walk was measured at baseline and 12 weeks. Exercise compliance, functional parameters, and quality of life (VascuQoL) were assessed by questionnaire. RESULTS: MWD, leg BF, and VascuQoL scores increased significantly, while resting HR, exercise HR, and end of walk rate-pressure-product (RPP) decreased significantly after 12 weeks. Exercise compliance was significantly correlated with increase in MWD (r=0.89, p<0.001) and QOL score improvement (r=0.61, p<0.001). CONCLUSIONS: This supported but unsupervised exercise programme generated improvements in walking distance and leg blood flow without detectable increases in cardiorespiratory work. Exercise compliance is related to MWD and VascuQoL score in a dose-response manner.
A J Roberts; E B Roberts; K Sykes; L De Cossart; P Edwards; D Cotterrell
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Publication Detail:
Type:  Journal Article     Date:  2008-06-10
Journal Detail:
Title:  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery     Volume:  36     ISSN:  1532-2165     ISO Abbreviation:  Eur J Vasc Endovasc Surg     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-19     Completed Date:  2008-09-16     Revised Date:  2009-03-31    
Medline Journal Info:
Nlm Unique ID:  9512728     Medline TA:  Eur J Vasc Endovasc Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  319-24     Citation Subset:  IM    
Research Laboratory, Sports and Exercise Science Department, University of Chester, Chester, UK.
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MeSH Terms
Cohort Studies
Exercise Therapy*
Intermittent Claudication / physiopathology,  therapy*
Middle Aged
Quality of Life
Recovery of Function
Comment In:
Eur J Vasc Endovasc Surg. 2009 Mar;37(3):370; author reply 370-1   [PMID:  18993087 ]

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