| Physiological effects of posture on mask ventilation in awake stable chronic hypercapnic COPD patients. | |
| | |
MedLine Citation:
|
PMID: 10543269 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Stable chronic hypercapnic patients are often prescribed long-term mask noninvasive pressure support ventilation (NPSV). There is a lack of information on the effects of posture on NPSV. Therefore posture induced changes in physiological effects of NPSV in awake stable chronic hypercapnic patients were evaluated. In 12 awake chronic obstructive pulmonary disease (COPD) patients breathing pattern, respiratory muscles, mechanics and dyspnoea (by visual analogue scale: VAS) were evaluated during spontaneous breathing (SB) in sitting posture and during NPSV in sitting, supine and lateral positions randomly assigned. Arterial blood gases were evaluated during SB and at the end of the last NPSV session (whatever the posture). As expected NPSV resulted in a significant improvement in carbon dioxide tension in arterial blood (Pa,CO2) (from 7.4+/-0.85 to 6.9+/-0.7 kPa). When compared with SB, sitting NPSV resulted in a significant increase in tidal volume and minute ventilation and in a significant decrease in breathing frequency. Inspiratory muscle effort as assessed by oesophageal pressure swings and pressure-time product per minute (from 14+/-4.8 to 6.2+/-3.5 cmH2O, and from 240+/-81 to 96+/-60 cmH2O x s x min(-1) respectively), intrinsic dynamic positive end expiratory pressure (from 2.7+/-2.3 to 1.4+/-1.3 cmH2O) and expiratory airway resistance (from 18+/-7 to 5+/-3 cmH2O x L x s(-1)) decreased during sitting NPSV, whereas VAS did not change. Changing posture did not significantly affect any parameter independently of the patients weight, whether obese or not. In awake stable hypercapnic chronic obstructive pulmonary disease patients changing posture does not significantly influence breathing pattern and respiratory muscles during noninvasive pressure support ventilation suggesting that mask ventilation may be performed in different positions without any relevant difference in its effectiveness. |
| | |
Authors:
|
R Porta; M Vitacca; E Clini; N Ambrosino |
Related Documents
:
|
4055589 - Effect of high-frequency ventilation on gas exchange and pulmonary vascular resistance ... 21526339 - Compression leggings modestly affect cardiovascular but not cerebrovascular responses t... 21434999 - Repeatability, reproducibility, and effect of head position on central venous pressure ... 4059689 - The effect of the phase relationship between the arterial blood gas oscillations and ce... 705069 - Occlusion pressure in acute bronchospasm induced by methylcholine. 7874909 - Cardiorespiratory effects of perfluorocarbon-associated gas exchange at reduced oxygen ... 10981559 - Candesartan cilexetil and renal hemodynamics in hypertensive patients. 7933059 - Effects of hypertonic saline on myocardial contractility in anaesthetized pigs. 12937519 - Elevated anterior compartment pressure in the leg after creatine supplementation: a con... |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology Volume: 14 ISSN: 0903-1936 ISO Abbreviation: Eur. Respir. J. Publication Date: 1999 Sep |
Date Detail:
|
Created Date: 1999-12-02 Completed Date: 1999-12-02 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8803460 Medline TA: Eur Respir J Country: DENMARK |
Other Details:
|
Languages: eng Pagination: 517-22 Citation Subset: IM; S |
Affiliation:
|
Salvatore Maugeri Foundation IRCCS: Pulmonary Department Medical Centre of Gussago, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Airway Resistance Blood Gas Analysis Esophagus / physiopathology Female Humans Hypercapnia / physiopathology, therapy* Laryngeal Masks* Lung Diseases, Obstructive / physiopathology, therapy* Male Middle Aged Positive-Pressure Respiration / methods* Posture / physiology* Pressure Pulmonary Ventilation Respiratory Muscles / physiopathology Treatment Outcome Wakefulness |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Response of respiratory motor output to varying pressure in mechanically ventilated patients.
Next Document: Serial measurements of exhaled nitric oxide during exacerbations of chronic obstructive pulmonary di...