| Physiological effects of caffeine, epigallocatechin-3-gallate, and exercise in overweight and obese women. | |
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MedLine Citation:
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PMID: 20962916 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to evaluate the combined effects of a 10-week exercise program with ingestion of caffeine and epigallocatechin-3-gallate (EGCG) on body composition, cardiovascular fitness, and strength in overweight and obese women. In a double-blind, placebo-controlled approach, overweight and obese women (n = 27) were randomly assigned to treatment groups with exercise (an active-supplementing group with exercise (EX-Act) and a placebo group with exercise (EX-PL)) or without exercise (an active-supplementing group without exercise (NEX-Act) and a placebo group without exercise (NEX-PL)). All participants consumed 1 drink per day for 10 weeks; EX-Act and EX-PL participated in a concurrent endurance and resistance training program. Changes in body composition were assessed using a 4-compartment model. Changes in muscle mass (MM) were evaluated using a DXA-derived appendicular lean-soft tissue equation. There was a significant time × treatment interaction for MM (p = 0.026) and total cholesterol (TC) (p = 0.047), and a significant time × training interaction for peak oxygen consumption (p = 0.046) and upper-body and lower-body strength (p < 0.05). Significant differences between the EX groups and NEX groups for percentage change in MM and peak oxygen consumption, and upper-body and lower-body strength, were revealed. Clinical markers for hepatic and renal function revealed no adverse effects. TC significantly decreased for the active-supplementing groups (EX-Act, NEX-Act). The current study suggests that implementing a caffeine-EGCG-containing drink prior to exercise may improve MM, fitness, and lipid profiles in overweight women. |
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Authors:
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Abbie E Smith; Christopher M Lockwood; Jordan R Moon; Kristina L Kendall; David H Fukuda; Sarah E Tobkin; Joel T Cramer; Jeffrey R Stout |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme Volume: 35 ISSN: 1715-5312 ISO Abbreviation: Appl Physiol Nutr Metab Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-21 Completed Date: 2010-12-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101264333 Medline TA: Appl Physiol Nutr Metab Country: Canada |
Other Details:
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Languages: eng Pagination: 607-16 Citation Subset: IM |
Affiliation:
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Department of Health and Exercise Science, University of Oklahoma, 1401 Asp Avenue, Norman, OK 73019, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Antioxidants / administration & dosage Body Composition / drug effects Caffeine / administration & dosage* Cardiovascular Physiological Processes / drug effects Catechin / administration & dosage, analogs & derivatives* Combined Modality Therapy Exercise / physiology* Female Humans Lipids / blood Middle Aged Obesity / drug therapy*, physiopathology Phosphodiesterase Inhibitors / administration & dosage Physical Endurance / drug effects* Physical Fitness / physiology Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Lipids; 0/Phosphodiesterase Inhibitors; 154-23-4/Catechin; 58-08-2/Caffeine; 989-51-5/epigallocatechin gallate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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