Document Detail

Physiological dead space & arterial to end-tidal CO2 difference under controlled normocapnic ventilation in young anaesthetised subjects.
MedLine Citation:
PMID:  1906429     Owner:  NLM     Status:  MEDLINE    
Physiological dead space and its components were determined in 27 young, otherwise healthy anaesthetised individuals before start of surgery. A squarewave inspiratory flow pattern and an end inspiratory pause (25 and 10% of cycle time respectively) were used at a respiratory rate of around 16 bpm with minute ventilation adjusted to maintain normocapnia. The physiological dead space was found to be 2.23 ml/kg with anatomical dead space forming 110.66 +/- 27.55 ml out of 125.55 +/- 27.06 ml. While VD alv was positively correlated to pause pressure, VD ant was correlated to age, weight, and body surface area. Mean arterial end tidal carbon dioxide difference was quite low (0.24 +/- 0.44 kPa).
G D Puri; R K Venkataraman; H Singh; S K Jindal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Indian journal of medical research     Volume:  94     ISSN:  0971-5916     ISO Abbreviation:  Indian J. Med. Res.     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-08-20     Completed Date:  1991-08-20     Revised Date:  2013-04-18    
Medline Journal Info:
Nlm Unique ID:  0374701     Medline TA:  Indian J Med Res     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  41-6     Citation Subset:  IM    
Department of Anaesthesiology, Postgraduate Institute of Medical Education & Research, Chandigarh.
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MeSH Terms
Anesthesia, General*
Carbon Dioxide / blood*
Middle Aged
Reference Values
Respiratory Dead Space*
Tidal Volume
Reg. No./Substance:
124-38-9/Carbon Dioxide

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