Document Detail

Physiological and behavioral indices of emotion dysregulation as predictors of outcome from cognitive behavioral therapy and acceptance and commitment therapy for anxiety.
MedLine Citation:
PMID:  25199454     Owner:  NLM     Status:  Publisher    
BACKGROUND AND OBJECTIVES: Identifying for whom and under what conditions a treatment is most effective is an essential step toward personalized medicine. The current study examined pre-treatment physiological and behavioral variables as predictors and moderators of outcome in a randomized clinical trial comparing cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT) for anxiety disorders.
METHODS: Sixty individuals with a DSM-IV defined principal anxiety disorder completed 12 sessions of either CBT or ACT. Baseline physiological and behavioral variables were measured prior to entering treatment. Self-reported anxiety symptoms were assessed at pre-treatment, post-treatment, and 6- and 12-month follow-up from baseline.
RESULTS: Higher pre-treatment heart rate variability was associated with worse outcome across ACT and CBT. ACT outperformed CBT for individuals with high behavioral avoidance. Subjective anxiety levels during laboratory tasks did not predict or moderate treatment outcome.
LIMITATIONS: Due to small sample sizes of each disorder, disorder-specific predictors were not tested. Future research should examine these predictors in larger samples and across other outcome variables.
CONCLUSIONS: Lower heart rate variability was identified as a prognostic indicator of overall outcome, whereas high behavioral avoidance was identified as a prescriptive indicator of superior outcome from ACT versus CBT. Investigation of pre-treatment physiological and behavioral variables as predictors and moderators of outcome may help guide future treatment-matching efforts.
Carolyn D Davies; Andrea N Niles; Andre Pittig; Joanna J Arch; Michelle G Craske
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-23
Journal Detail:
Title:  Journal of behavior therapy and experimental psychiatry     Volume:  46C     ISSN:  1873-7943     ISO Abbreviation:  J Behav Ther Exp Psychiatry     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-9-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0245075     Medline TA:  J Behav Ther Exp Psychiatry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  35-43     Citation Subset:  -    
Copyright Information:
Copyright © 2014. Published by Elsevier Ltd.
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