Document Detail

Physiological adaptations of pregnancy affecting the nervous system.
MedLine Citation:
PMID:  17940919     Owner:  NLM     Status:  MEDLINE    
Physiological adaptations of pregnancy affect neurological function in health and disease. Women often experience self-limited sensory abnormalities that resolve shortly after delivery. More important, pregnancy can predispose to the onset or deterioration of permanent neurological disorders. Lastly, complications of pregnancy may develop in patients with preexisting neurological disease. Therefore, a basic knowledge of reproductive physiology can guide clinicians in the diagnosis and management of the pregnant patient with neurological symptoms. This clinical review highlights the modifications that affect the nervous system, including neuroanatomy, reproductive endocrinology, immunology, systemic and cerebral circulations, metabolism, and coagulation profile. The widespread role of sex steroids in many of these adaptations is addressed to illustrate the complex interactions of human reproductive biology.
Lydia K Lee
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in neurology     Volume:  27     ISSN:  0271-8235     ISO Abbreviation:  Semin Neurol     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-10-17     Completed Date:  2008-01-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8111343     Medline TA:  Semin Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  405-10     Citation Subset:  IM    
Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
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MeSH Terms
Adaptation, Physiological / physiology*
Nervous System* / anatomy & histology,  metabolism
Pregnancy / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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