Document Detail

Physiologic, metabolic and mediator responses in posttrauma ARDS and sepsis: is oxygen debt a critical initiating factor?
MedLine Citation:
PMID:  9444608     Owner:  NLM     Status:  MEDLINE    
Posttrauma adult respiratory distress syndrome (ARDS) and sepsis initiate complex humoral and cellular inflammatory responses that initially effect the microvascular system, but rapidly extend to involve and modulate the solid organ metabolic response. It is discussed whether the interaction between these cellular processes and the organs which they involve appear to be initiated by the trauma induced oxygen debt.
J H Siegel
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society     Volume:  48     ISSN:  0867-5910     ISO Abbreviation:  J. Physiol. Pharmacol.     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-03-03     Completed Date:  1998-03-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9114501     Medline TA:  J Physiol Pharmacol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  559-85     Citation Subset:  IM    
Department of Anatomy, Cell Biology and Injury Sciences, New Jersey Medical School, UMDNJ, Newark, USA.
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MeSH Terms
Anoxia / etiology,  physiopathology*
Lung / physiopathology*
Respiratory Distress Syndrome, Adult / etiology,  physiopathology*
Systemic Inflammatory Response Syndrome / complications,  physiopathology*
Wounds and Injuries / complications,  physiopathology*

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