| Physiologic evaluation of different levels of assistance during noninvasive ventilation delivered through a helmet. | |
| | |
MedLine Citation:
|
PMID: 16236976 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To evaluate the effects of various levels of pressure support (PS) during noninvasive ventilation delivered through a helmet on breathing pattern, inspiratory effort, CO2 rebreathing, and comfort. DESIGN: Physiologic study. SETTING: University-affiliated hospital. PATIENTS AND PARTICIPANTS: Eight healthy volunteers. INTERVENTIONS: Volunteers received ventilation through a helmet with four different PS/positive end-expiratory pressure combinations (5/5 cm H2O, 10/5 cm H2O, 15/5 cm H2O, and 10/10 cm H2O) applied in random order. MEASUREMENTS AND RESULTS: The ventilatory respiratory rate, esophageal respiratory rate (RRpes), airway pressure, esophageal pressure tracings, esophageal swing, and pressure-time product (PTP) [PTP per breath, PTP per minute, and PTP per liter] were evaluated. We also measured the partial pressure of inspired CO2 (Pi(CO2)) at the airway opening, mean partial pressure of expired CO2 (Pe(CO2)), CO2 production (V(CO2)), minute ventilation (V(E)) delivered to the helmet (V(E)h), and the true inspired V(E). By subtracting V(E) from V(E)h, we obtained the Ve washing the helmet (V(E)wh). A visual analog scale (from 0 to 10) was used to evaluate comfort. Compared to spontaneous breathing, different levels of PS progressively increased tidal volume (V(T)) and decreased RRpes, reducing inspiratory effort. The increased levels of assistance did not produce significant changes in Pi(CO2), end-tidal CO2, and V(CO2). Pe(CO2) had a slight decrease when increasing the level of PS from 5 to 10 cm H2O (p < 0.05). Despite the presence of constant values of Ve, the increase of PS produced an increase in V(E)wh, without significant differences comparing 10 cm H2O and 15 cm H2O of PS. The subjects had a slight but not significant increase in discomfort by augmenting the level of assistance. At the highest level of PS (15 cm H2O), the discomfort was significantly higher (p < 0.001) than at the other levels of assistance. CONCLUSION: In volunteers, the helmet is efficient in ventilation, allowing a Vt increase and RRpes reduction. A significant discomfort was present only at the highest level of assistance; however, it did not affect patient/ventilator interaction. |
| | |
Authors:
|
Roberta Costa; Paolo Navalesi; Massimo Antonelli; Franco Cavaliere; Andrea Craba; Rodolfo Proietti; Giorgio Conti |
Related Documents
:
|
15109926 - Day/night pattern of arterial blood gases in the cow. 15027686 - Cardiovascular effects of insufflation of the abdomen with carbon dioxide in standing h... 18458036 - Tidal volume threshold for colorimetric carbon dioxide detectors available for use in n... 16930886 - Hot stage extrusion of p-amino salicylic acid with ec using co2 as a temporary plastici... 2455116 - Effects of different sodium intakes on the antihypertensive and renal effects of single... 17670366 - The effects of cardiac cooling under surface-induced hypothermia on the cardiac functio... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Chest Volume: 128 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 2005 Oct |
Date Detail:
|
Created Date: 2005-10-20 Completed Date: 2005-11-21 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0231335 Medline TA: Chest Country: United States |
Other Details:
|
Languages: eng Pagination: 2984-90 Citation Subset: AIM; IM |
Affiliation:
|
Dipartimento di Anestesia e Rianimazione, Università Cattolica del S. Cuore, Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Carbon Dioxide / analysis Equipment Design Female Head Protective Devices* Humans Intermittent Positive-Pressure Ventilation / instrumentation, methods Male Positive-Pressure Respiration / instrumentation*, methods Reference Values Respiratory Physiological Phenomena |
| Chemical | |
Reg. No./Substance:
|
124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pneumothorax-associated pleural eosinophilia in mice is interleukin-5 but not interleukin-13 depende...
Next Document: Effects of spontaneous breathing during airway pressure release ventilation on respiratory work and ...