Document Detail


Physician-pharmacist co-management and 24-hour blood pressure control.
MedLine Citation:
PMID:  23614849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objectives of this study were to compare indices of 24-hour blood pressure (BP) following a physician-pharmacist collaborative intervention and to describe the associated changes in antihypertensive medications. This was a secondary analysis of a prospective, cluster-randomized clinical trial conducted in 6 family medicine clinics randomized to co-managed (n=3 clinics, 176 patients) or control (n=3 clinics, 198 patients) groups. Mean ambulatory systolic BP (SBP) was significantly lower in the co-managed vs the control group: daytime BP 122.8 mm Hg vs 134.4 mm Hg (P<.001); nighttime SBP 114.8 mm Hg vs 123.7 mm Hg (P<.001); and 24-hour SBP 120.4 mm Hg vs 131.8 mm Hg (P<.001), respectively. Significantly more drug changes were made in the co-managed than in the control group (2.7 vs 1.1 changes per patient, P<.001), and there was greater diuretic use in co-managed patients (79.6% vs 62.6%, P<.001). Ambulatory BPs were significantly lower for the patients who had a diuretic added during the first month compared with those who never had a diuretic added (P<.01). Physician-pharmacist co-management significantly improved ambulatory BP compared with the control group. Antihypertensive drug therapy was intensified much more for patients in the co-managed group.
Authors:
Ziqian Chen; Michael E Ernst; Gail Ardery; Yinghui Xu; Barry L Carter
Related Documents :
24637789 - Rationale, study design, and implementation of the acs1 study: effect of azilsartan on ...
8799659 - Predictors of transcutaneous oxygen tension in the lower limbs of diabetic subjects.
8946179 - Plantar foot pressures during treadmill walking with high-heel and low-heel shoes.
7965879 - Pressure redistribution by molded inserts in diabetic footwear: a pilot study.
9726299 - Foraminal pressure changes during intervertebral distraction simulating anterior cervic...
20863099 - Lubricated tribology of a eutectic aluminium-silicon alloy in the ultra-mild wear and m...
6839919 - Dynamic foot pressure and other studies as diagnostic and management aids in diabetic n...
8724019 - Hyperglycaemia affects proximal gastric motor and sensory function in normal subjects.
2022579 - Aerosolized surfactant treatment of preterm lambs.
Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2013-02-12
Journal Detail:
Title:  Journal of clinical hypertension (Greenwich, Conn.)     Volume:  15     ISSN:  1751-7176     ISO Abbreviation:  J Clin Hypertens (Greenwich)     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-04-25     Completed Date:  2013-10-22     Revised Date:  2014-05-28    
Medline Journal Info:
Nlm Unique ID:  100888554     Medline TA:  J Clin Hypertens (Greenwich)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  337-43     Citation Subset:  IM    
Copyright Information:
© 2013 Wiley Periodicals, Inc.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Antihypertensive Agents / therapeutic use*
Blood Pressure / drug effects*
Blood Pressure Monitoring, Ambulatory / methods*
Female
Humans
Hypertension / prevention & control*
Male
Middle Aged
Patient Care Team / organization & administration*
Pharmacists*
Physicians*
Primary Health Care / methods
Prospective Studies
Grant Support
ID/Acronym/Agency:
5U18HSO16094//PHS HHS; HL069801/HL/NHLBI NIH HHS; HL070740/HL/NHLBI NIH HHS; R01 HL070740/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Antihypertensive Agents
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Masked hypertension and atherogenesis: the impact of apelin and relaxin plasma levels.
Next Document:  Predicting the risk of incident hypertension in a Korean middle-aged population: Korean genome and e...