| Physical training in patients with chronic heart failure of ischemic origin: effect on exercise capacity and left ventricular remodeling. | |
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MedLine Citation:
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PMID: 17301632 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Physical training is a well-known complementary treatment for chronic heart failure (CHF); however, many aspects require further studies. One of them is the impact on remodeling of the left ventricle (LV). The purpose of this study was to evaluate the effect of 6 months of training on LV, exercise capacity and safety issues in patients with ischemic CHF. METHODS: Fifty patients (mean age 60.1+/-9.2 years) with ischemic CHF, New York Heart Association (NYHA) classification class II and III and left ventricular ejection fraction (LVEF) <or=35% were randomized into groups: undergoing 6-month training (25 patients) and not trained (25 patients). In both groups at baseline and at 6 months a cardiopulmonary exercise test and magnetic resonance imaging (MRI) with evaluation of LV were performed. Training was limited by the achievement of 80% of the predicted heart rate at VO2peak achieved at the baseline cardiopulmonary exercise test. RESULTS: All patients completed the 6-month observation. No serious adverse events were found in either group. Exercise capacity improved only in the trained group (VO2peak increased by 31%). At 6 months in the trained group there was a tendency towards an improvement in some LV parameters: ejection fraction, end-diastolic volume and wall motion score index (WMSI), whereas an opposite trend was seen in the controls (P<0.05, P<0.05 and P<0.01 for comparison of LVEFs, end-diastolic volumes and WMSIs, respectively). CONCLUSIONS: Six-month training in ischemic CHF patients is a safe modality. Training improves exercise capacity. There was no negative impact on LV morphology, and a trend towards improvement of functional parameters on MRI may suggest an anti-remodeling effect of training in patients with ischemic CHF. |
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Authors:
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Artur Klecha; Kalina Kawecka-Jaszcz; Bogumiła Bacior; Aleksandra Kubinyi; Mieczysław Pasowicz; Piotr Klimeczek; Robert Banyś |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology Volume: 14 ISSN: 1741-8267 ISO Abbreviation: Eur J Cardiovasc Prev Rehabil Publication Date: 2007 Feb |
Date Detail:
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Created Date: 2007-02-15 Completed Date: 2007-05-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101192000 Medline TA: Eur J Cardiovasc Prev Rehabil Country: England |
Other Details:
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Languages: eng Pagination: 85-91 Citation Subset: IM |
Affiliation:
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I Cardiac Department, Jagiellonian University Medical College, Kraków, Poland. arturklecha@poczta.onet.pl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cardiac Output, Low / complications*, therapy* Chronic Disease Exercise Test Exercise Therapy Exercise Tolerance / physiology* Female Humans Magnetic Resonance Imaging Male Middle Aged Myocardial Ischemia / complications*, therapy* Quality of Life Treatment Outcome Ventricular Function, Left / physiology* Ventricular Remodeling* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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