Document Detail

Physical training effects in renal transplant recipients.
MedLine Citation:
PMID:  19788449     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Several studies demonstrated the benefits of rehabilitation in uraemic patients. This study evaluates physical and psychosocial effects of exercise on renal transplant recipients (RTRs).
PATIENTS AND METHODS: Eight RTRs were evaluated before and after an exercise training consisting of thirty 40-minute sessions, three times a week, performed with the interval training technique.
RESULTS: Hospital Anxiety and Depression Scale (HADS) significantly decreased (p<0.04 and <0.008, respectively). Quality of life mean scores (SF-36 test) significantly increased (p<0.000). No differences were recorded for muscle and fat mass, maximal explosive power of the lower limbs, alkaline and acid phosphatase, parathormone (PTH), myoglobin, lipoprotein-A, glomerular filtration rate (GFR), at rest heart rate, and cardiac troponin. IL-6 decreased from 2.8±0.6 to 1.7±0.5 pg/mL (p<0.01). Resting MAP fell from 112±4 to 99±3 mmHg (p<0.02). The metabolic threshold rose from 33±4 to 43±5% (p<0.033). The blood lactate level at peak exercise increased from 5.2±0.9 to 6.2±0.7 mmol/L (p<0.012). The maximum oxygen uptake increased from 1200±210 to 1359±202 mL/min (p<0.05), iso-load oxygen uptake decreased from 1110±190 to 1007±187 mL/min (p<0.034). The maximum working capacity increased from 90±14 to 115±15 watts (p<0.000).
CONCLUSION: This study suggests that an appropriate dose of physical training is a useful, safe and non-pharmacologic contribution to RTR treatment.
G Romano; R Simonella; E Falleti; N Bortolotti; E Deiuri; G Antonutto; S De Vita; G F Ferraccioli; D Montanaro
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical transplantation     Volume:  24     ISSN:  1399-0012     ISO Abbreviation:  Clin Transplant     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-09-24     Completed Date:  2011-02-01     Revised Date:  2012-03-14    
Medline Journal Info:
Nlm Unique ID:  8710240     Medline TA:  Clin Transplant     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  510-4     Citation Subset:  IM    
Copyright Information:
© 2009 John Wiley & Sons A/S.
S.M. Misericordia University Hospital, Udine, Italy.
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MeSH Terms
Exercise Therapy*
Glomerular Filtration Rate
Graft Rejection / prevention & control*,  psychology*
Kidney Transplantation*
Middle Aged
Prospective Studies
Treatment Outcome

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