Document Detail

Physical properties of acetic acid vital in evaluating the cervix for neoplastic changes.
MedLine Citation:
PMID:  11055488     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: In a "developing country" the need exists for an inexpensive, simplistic yet sensitive screening procedure which furthermore, allows for the immediate referral of patients. Research has indicated that the acetic acid test is a most viable option. Screening, however, often occurs in less than ideal conditions thus implying the exposure of the acetic acid to various fluctuating elements. OBJECTIVE: Determining the influence of temperature, time and humidity on the pH of a 5% acetic acid solution. METHOD: The effect of temperature, time and humidity on the pH of a 5% acetic acid solution was determined under controlled laboratory conditions utilizing the calculated molar conductance and dissociation constant. RESULTS: The pH of the 5% acetic acid solution remained a constant throughout exposure to the various elements. DISCUSSION: The results imply that the quality of acetic acid, on which many alternative screening methods and colposcopy are based, remains stable under varying conditions. This is important when screening is implemented in less than ideal conditions utilizing cervicography or the acetic acid test which are primarily dependent on acetic acid.
I C Niemand; H S Cronjè; J M Botha
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of gynaecological oncology     Volume:  21     ISSN:  0392-2936     ISO Abbreviation:  Eur. J. Gynaecol. Oncol.     Publication Date:  2000  
Date Detail:
Created Date:  2001-01-31     Completed Date:  2001-03-15     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8100357     Medline TA:  Eur J Gynaecol Oncol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  380-2     Citation Subset:  IM    
Department of Obstetrics & Gynaecology, University of the Orange Free State, Bloemfontein, South Africa.
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MeSH Terms
Acetic Acid / chemistry*,  diagnostic use*
Developing Countries
Drug Stability
Hydrogen-Ion Concentration
Mass Screening / methods*
Sensitivity and Specificity
Uterine Cervical Neoplasms / diagnosis*
Reg. No./Substance:
64-19-7/Acetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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