| Physical (in)activity over 20y in adulthood: Associations with adult lipid levels in the 1958 British birth cohort. | |
| | |
MedLine Citation:
|
PMID: 21855876 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
OBJECTIVES: To investigate associations between physical (in)activity at different life-stages and lipids in mid-adulthood, examining the role of potential confounding and mediating factors, such as adiposity. METHODS: Data from the 1958 British birth cohort (n=7824) were examined. Using linear regression, we analysed prospectively reported frequency of activity and TV-viewing (23, 33, 42 and 45y) in relation to total, LDL-, HDL-cholesterol and triglycerides, at 45y. RESULTS: Activity at different ages was associated with HDL-cholesterol and triglycerides at 45y: e.g. in men, a 1 day/week greater activity frequency at 42y was associated with 0.006mmol/L higher HDL-cholesterol and 1.4% lower triglycerides. Most associations attenuated, but were not entirely explained by adjustment for covariates (life-styles and socio-economic factors): e.g. among men, the estimated 2.0% lower triglycerides per 1 day/week greater frequency at 33y reduced to 1.8% after adjustment. Among women, though not men, activity at both 23 and 45y contributed cumulatively to HDL-cholesterol. For sedentary behaviour, associations were found for sitting at work: a 1h/day greater sitting among men was associated with a 0.012mmol/L lower HDL-cholesterol after adjustment for covariates. Associations were seen for TV-viewing: e.g. in men, a 0.04mmol/L lower HDL-cholesterol and 5.9% higher triglycerides per hour/day greater TV-viewing at 45y, attenuated, respectively, to 0.03mmol/L and 4.6% after adjustment for covariates. Associations attenuated further after adjustment for current BMI. Associations for total and LDL-cholesterol were less consistent. CONCLUSION: Activity and sedentary behaviour at different adult ages were associated with HDL-cholesterol and triglycerides in mid-adulthood. Associations were partly mediated by other life-style factors and by BMI. |
| | |
Authors:
|
Myung Ki; Theodora Pouliou; Leah Li; Chris Power |
Related Documents
:
|
2912016 - Sustained depression of the resting metabolic rate after massive weight loss. 19470086 - The diet, obesity and genes (diogenes) dietary study in eight european countries - a co... 20670466 - Long-term effects on haemostatic variables of three ad libitum diets differing in type ... 16232316 - Diet induced weight loss accelerates onset of negative alliesthesia in obese women. 9625096 - Copper absorption, excretion, and retention by young men consuming low dietary copper d... 988546 - Functional and anatomical characteristics of the nerve-brown adipose interaction in the... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-7-30 |
Journal Detail:
|
Title: Atherosclerosis Volume: - ISSN: 1879-1484 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
|
Created Date: 2011-8-22 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0242543 Medline TA: Atherosclerosis Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011. Published by Elsevier Ireland Ltd. |
Affiliation:
|
MRC Centre of Epidemiology for Child Health, Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Glucosamine-supplementation promotes endoplasmic reticulum stress, hepatic steatosis and accelerated...
Next Document: Influence of carrier solution ionic strength and injected sample load on retention and recovery of n...