Document Detail

Physical exertion at work and the risk of preterm delivery and small-for-gestational-age birth.
MedLine Citation:
PMID:  16319253     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess whether exposure to standing, lifting, night work, or long work hours during 3 periods of pregnancy are associated with an increased risk of preterm or small-for-gestational-age birth. METHODS: The Pregnancy, Infection and Nutrition study is a prospective cohort with a nested case-control component that was conducted through clinic and hospital settings in Central North Carolina. A total of 1,908 women pregnant with a singleton gestation were recruited during prenatal visits from January 1995 through April 2000 and provided information during telephone and face-to-face interviews about physical exertion for the 2 longest-held jobs during pregnancy. RESULTS: No significant elevations in preterm delivery were observed among women who lifted repeatedly or stood at least 30 hours per week, with no changes in risk estimates over the course of pregnancy. A 50% elevation in the risk of preterm delivery (relative risk 1.5, 95% confidence interval 1.0-2.0; first trimester) was observed among women who reported working at night (10:00 PM to 7:00 AM), whereas a 40% reduction in risk was observed among women working at least 46 hours per week (relative risk 0.6, 95% confidence interval 0.4-0.9; first trimester), regardless of period of exposure. No elevations in small-for-gestational-age birth were observed among women exposed to any of the 4 types of occupational exertion. CONCLUSION: Physically demanding work does not seem to be associated with adverse pregnancy outcomes, whereas working at night during pregnancy may increase the risk of preterm delivery. Studies to examine the effect of shift work on uterine activity would help to clarify the possibility of a causal effect on preterm birth.
Lisa A Pompeii; David A Savitz; Kelly R Evenson; Bonnie Rogers; Michael McMahon
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  106     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-12-01     Completed Date:  2006-02-22     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1279-88     Citation Subset:  AIM; IM    
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, USA.
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MeSH Terms
Age Distribution
Case-Control Studies
Cohort Studies
Confidence Intervals
Follow-Up Studies
Gestational Age
Infant, Newborn
Infant, Premature
Infant, Small for Gestational Age*
Maternal Age
Obstetric Labor, Premature / epidemiology*,  etiology*
Odds Ratio
Physical Exertion*
Prospective Studies
Risk Assessment
Women, Working*
Work Schedule Tolerance
Grant Support
Comment In:
Evid Based Med. 2006 Oct;11(5):156   [PMID:  17213158 ]
Evid Based Nurs. 2006 Oct;9(4):121   [PMID:  17076021 ]

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