Document Detail

Physical activity during pregnancy is associated with reduced fasting insulin--the Pilot Pregnancy and Active Living Study.
MedLine Citation:
PMID:  20230322     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine the relationship between physical activity during pregnancy and fasting plasma insulin measured in the second trimester.
STUDY DESIGN AND METHODS: We conducted a pilot prospective cohort study of 69 overweight or obese women who were enrolled before 20 weeks of gestation at an obstetric clinic in Columbia, South Carolina in 2006-2007. At 24-28 weeks of gestation, fasting blood samples were collected and physical activity from the 3 months prior to the visit was assessed using a validated Pregnancy Physical Activity Questionnaire.
RESULTS: Total energy expenditure (EE) in this population was attributable to sedentary activities (24.4%) and to physical activities of different intensities (light: 44.8%, moderate: 30.2%, and vigorous: 0.6%). By type, total EE mainly came from household/caregiving activities (58.9%) with a small proportion from exercise (3.8%). After adjusting for confounders, the mean fasting insulin values across the quartiles of total EE (least to most) were 17.3, 13.0, 12.1, and 9.6 uIU/ml (P for trend=0.01).
CONCLUSION: Our findings suggest that increased total physical activity is associated with reduced fasting insulin levels in overweight or obese pregnant women.
Ji-Hong Liu; Elizabeth J Mayer-Davis; Russell R Pate; Alexa E Gallagher; Janice L Bacon
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  23     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-13     Completed Date:  2011-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  1249-52     Citation Subset:  IM    
Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA.
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MeSH Terms
Cohort Studies
Energy Metabolism / physiology*
Insulin / blood*
Obesity / blood*
Pilot Projects
Pregnancy Trimester, Second
Young Adult
Reg. No./Substance:

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