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Physical Inactivity and Long-Term Rates of Community-Acquired Sepsis.
MedLine Citation:
PMID:  24768917     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE:: The authors sought to determine the association between physical inactivity (characterized by exercise and television watching levels) and long-term rates of community-acquired sepsis.
METHODS:: Population-based cohort study of 30,183 adult (≥45years) community-dwelling participants. Subjects reported weekly exercise (low=none, medium=1-3 times/week, high=≥4 times/week) and daily television watching (low=<1hour/day, medium=1-3 hours/day, high=≥4hours/day) levels. The authors evaluated the association between exercise, television watching and rates of sepsis, defined as hospital treatment for a serious infection with ≥2 Systemic Inflammatory Response Syndrome (SIRS) criteria.
RESULTS:: Among 30,183 participants, 1,500 experienced a sepsis event. Reported weekly exercise was: high 8,798 (29.2%), medium 10,695 (35.4%), and low 10,240 (33.9%). Where available, reported daily television watching was: low 4,615 (19.6%), medium 11,587 (49.3%) and high 7,317 (31.1%). Decreased weekly exercise was associated with increased adjusted sepsis rates (high - referent; medium HR 1.02, 95% CI 0.96-1.20; low 1.33, 1.13-1.56). Daily television watching was not associated with sepsis rates. Sepsis rates were highest among those with both low exercise and high television watching levels (HR 1.49, 95% CI: 1.10-2.01).
CONCLUSIONS:: Physical inactivity may be associated with increased long-term rates of community-acquired sepsis.
Authors:
Henry E Wang; John Baddley; Russell Griffin; Suzanne Judd; George Howard; John Donnelly; Monika M Safford
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-4-23
Journal Detail:
Title:  Preventive medicine     Volume:  -     ISSN:  1096-0260     ISO Abbreviation:  Prev Med     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-4-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0322116     Medline TA:  Prev Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014. Published by Elsevier Inc.
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