Document Detail

Physical Exercise Alleviates ADHD Symptoms: Regional Deficits and Development Trajectory.
MedLine Citation:
PMID:  21850535     Owner:  NLM     Status:  Publisher    
The heterogeneous, chronic, and proliferating aspect of attention deficit hyperactivity disorder (ADHD) and comorbidities covers heritability, cognitive, emotional, motor, and everyday behavioral domains that place individuals presenting the condition at some considerable disadvantage. Disruption of "typical developmental trajectories" in the manifestation of gene-environment interactive predispositions implies that ADHD children and adolescents may continue to perform at defective levels as adults with regard to academic achievement, occupational enterprises, and interpersonal relationships, despite the promise of pharmacotherapeutic treatments. Physical exercise provides a plethora of beneficial effects against stress, anxiety, depression, negative affect and behavior, poor impulse control, and compulsive behavior concomitant with improved executive functioning, working memory and positive affect, as well as improved conditions for relatives and care-givers. Brain-derived neurotrophic factor, an essential element in normal brain development that promotes health-associated behaviors and quality-of-life, though reduced in ADHD, is increased markedly by the intervention of regular physical exercise. Functional, regional, and biomarker deficits, as well as hypothalamic-pituitary-adrenal disruptions, have been improved through regular and carefully applied exercise programs. In view of the complications involving ADHD with co-morbidities, such as obesity, the influence of regular physical exercise has not been found negligible. Physical exercise bestows a propensity for eventual manifestation of "redifferentiated" developmental trajectories that may equip ADHD adults with a prognosis that is more adaptive functionally, independent of the applications of other therapeutic agents and treatments.
Trevor Archer; Richard M Kostrzewa
Related Documents :
3264855 - Psychological factors influence the success of coronary artery surgery.
10639305 - Early symptom-limited exercise test for risk stratification in post menopausal women wi...
10149875 - Clinical applicability of echocardiographically detected regional wall-motion abnormali...
23749395 - Influence of pubertal stage on local sweating patterns of girls exercising in the heat.
21791015 - Attenuated relationship between cardiac output and oxygen uptake during high intensity ...
18802235 - Suggestions from the clinic ankle injuries: clinical observations.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-18
Journal Detail:
Title:  Neurotoxicity research     Volume:  -     ISSN:  1476-3524     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100929017     Medline TA:  Neurotox Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Psychology, University of Gothenburg, P.O. Box 500, 405 30, Gothenburg, Sweden,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparative effects of recombinant human activated protein C and dexamethasone in experimental septi...
Next Document:  Is there a role for high dose chemotherapy with hematopoietic stem cell rescue in patients with rela...