| Phylloquinone (vitamin K1) intakes and serum undercarboxylated osteocalcin levels in Irish postmenopausal women. | |
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MedLine Citation:
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PMID: 16611390 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Low phylloquinone (vitamin K1) intakes have been associated with low bone mineral density in older adults. Phylloquinone intakes and serum undercarboxylated osteocalcin (ucOC) levels were assessed in ninety-seven apparently healthy, free-living Irish women aged 50-75 years. Phylloquinone intakes were estimated using a detailed dietary history, which measured habitual food intakes from a typical 14 d period, and recently published food composition data for phylloquinone. Fasting serum ucOC was measured using an enzyme immunoassay. The median daily intake of phylloquinone in the group from all sources was 108.8 microg and from food sources only was 106.6 microg, indicating that approximately 99 % of the phylloquinone came from food. Vegetables and vegetable dishes contributed 67 % of the total phylloquinone intake, but further analysis showed that broccoli, cabbage and lettuce were the primary sources, making a total contribution of 44 %. Twenty per cent of the women had a phylloquinone intake below the UK recommendation of 1 microg/kg body weight per day and 34 % failed to meet the US Adequate Intake value of 90 microg/day. Mean serum ucOC levels in the women were 6.2 (SD 1.7) ng/ml and were predicted by phylloquinone intake (beta -2.20, generated from log-transformed phylloquinone intake data; P=0.04). On the basis of comparisons with both UK recommendations and US Adequate Intakes for phylloquinone, the habitual intakes of phylloquinone in a high proportion of Irish postmenopausal women may not be adequate. |
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Authors:
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Aoife Collins; Kevin D Cashman; Máiréad Kiely |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The British journal of nutrition Volume: 95 ISSN: 0007-1145 ISO Abbreviation: Br. J. Nutr. Publication Date: 2006 May |
Date Detail:
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Created Date: 2006-04-13 Completed Date: 2006-06-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: England |
Other Details:
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Languages: eng Pagination: 982-8 Citation Subset: IM |
Affiliation:
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Department of Food and Nutritional Sciences, University College, Cork, Ireland. collinsaoife@ucc.ie |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anthropometry Diet / statistics & numerical data Female Food Habits Humans Ireland Middle Aged Nutritional Requirements Osteocalcin / blood* Postmenopause / blood* Vegetables / chemistry Vitamin K 1 / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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104982-03-8/Osteocalcin; 84-80-0/Vitamin K 1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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