Document Detail

Phyllodes tumor of the vulva: Report of a rare case and review of the literature.
MedLine Citation:
PMID:  20514681     Owner:  NLM     Status:  MEDLINE    
Phyllodes tumor occurring in the vulva is extremely rare; only 6 cases have been previously reported in the literature. The histogenetic origin of this tumor is controversial as it is being debated whether such lesions evolve from ectopic breast tissue, cutaneous apocrine glands, and most recently, anogenital mammary-like gland. We report an 18-year-old Kuwaiti girl who presented with a painless mass in the left labium majus, which was subsequently excised. Microscopic examination revealed morphologic pattern characteristic of benign phyllodes tumor. Immunostaining demonstrated the presence of estrogen receptors and progesterone receptors in the epithelial component. We present this case to emphasize the importance of recognizing this uncommon lesion occurring at an extremely unusual site. We also discuss the histogenesis of phyllodes tumor and related lesions occurring in the anogenital region in light of the current literature along with a brief review of the previously reported cases of vulvar phyllodes tumor.
Abul Ala Syed Rifat Mannan; Mirza Kahvic; Amal Hassan Abdel Aziz
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  32     ISSN:  1533-0311     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-28     Completed Date:  2010-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  384-6     Citation Subset:  IM    
Departments of Pathology, Al Jahra Hospital, Kuwait city, Kuwait.
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MeSH Terms
Phyllodes Tumor / metabolism,  pathology*,  surgery
Receptors, Estrogen / biosynthesis
Receptors, Progesterone / biosynthesis
Vulvar Neoplasms / metabolism,  pathology*,  surgery
Young Adult
Reg. No./Substance:
0/Receptors, Estrogen; 0/Receptors, Progesterone

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