Document Detail


Phyciochemical properties and applications of Poly(lactic-co-glycolic acid) for use in bone regeneration.
MedLine Citation:
PMID:  23350707     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Poly(lactic-co-glycolic acid) (PLGA) is the most often used synthetic polymer within the field of bone regeneration owing to its biocompatibility and biodegradability. As a consequence, a large number of medical devices comprising PLGA have been approved for clinical use in humans by the American Food and Drug Administration. As compared to the homopolymers of lactic acid poly(lactic acid) and poly(glycolic acid), the co-polymer PLGA is much more versatile with respect to the control over degradation rate. As a material for bone regeneration, the use of PLGA has been extensively studied for application include as either scaffolds, coatings, fibers or micro- and nanospheres to meet various clinical requirements.
Authors:
Rosa Félixlanao; Anika M Jonker; Joop Wolke; John Jansen; Jan Cm van Hest; Sander Leeuwenburgh
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-25
Journal Detail:
Title:  Tissue engineering. Part B, Reviews     Volume:  -     ISSN:  1937-3376     ISO Abbreviation:  Tissue Eng Part B Rev     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101466660     Medline TA:  Tissue Eng Part B Rev     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Radboud University Nijmegen Medical Centre, Biomaterials, Philips van Leydenlaan 25, Nijmegen, Netherlands, 6525 EX , 0031243614071; R.FelixLanao@dent.umcn.nl.
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