Document Detail


Phototherapy for neonatal nonhemolytic hyperbilirubinemia. Analysis of rebound and indications for discontinuing therapy.
MedLine Citation:
PMID:  8324969     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Phototherapy, an effective treatment for neonatal indirect hyperbilirubinemia, has guidelines for its initiation but none for its discontinuation. In our study, phototherapy was begun at a mean age of 90 hours in 28 full-term and 30 preterm infants with indirect nonhemolytic hyperbilirubinemia. After three days, phototherapy was halted at a mean bilirubin concentration of 13.0 +/- 0.7 mg/dL in term and 10.7 +/- 1.2 mg/dL in preterm infants, levels higher than those used by other investigators. Bilirubin rebound then occurred at a mean of 12.5 hours to a level of 0.86 +/- 1.0 mg/dL in term and at a mean of 14.1 hours to a level of 0.83 +/- 0.56 mg/dL in preterm infants. No complications were observed nor was there a need for reinstitution of phototherapy. Based on these data, discontinuation of phototherapy at higher bilirubin concentrations and earlier home discharge than previously described appear harmless for both term and preterm neonates.
Authors:
L Lazar; A Litwin; P Merlob
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  32     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-08-11     Completed Date:  1993-08-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  264-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Neonatology, Beilinson Medical Center, Petah Tikva, Israel.
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MeSH Terms
Descriptor/Qualifier:
Bilirubin / blood
Female
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / blood,  therapy
Jaundice, Neonatal / blood,  therapy*
Male
Phototherapy / methods*
Recurrence
Time Factors
Chemical
Reg. No./Substance:
635-65-4/Bilirubin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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