Document Detail


Photostability of Isovaline and its Precursor 5-Ethyl-5- methylhydantoin Exposed to Simulated Space Radiations.
MedLine Citation:
PMID:  22312300     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Aqueous solutions of isovaline and its precursor molecule, 5-ethyl-5-methylhydantoin, were irradiated with ultraviolet and γ-ray photons, to evaluate their structural stability against space radiation. The degree of photolysis was measured and irradiation products were identified using chiral, reversed-phase and ion-exchange high-performance liquid chromatography. The experimental results show that the degree of photolysis of 5-ethyl-5-methylhydantoin is more significant than that of isovaline under ultraviolet light irradiation, while the results under γ-ray irradiation are the opposite. As the products of isovaline photolysis, aspartic acid, serine, glutamic acid and alanine were dominantly detected.
Authors:
Palash K Sarker; Jun-Ichi Takahashi; Yukinori Kawamoto; Yumiko Obayashi; Takeo Kaneko; Kensei Kobayashi
Publication Detail:
Type:  Journal Article     Date:  2012-01-17
Journal Detail:
Title:  International journal of molecular sciences     Volume:  13     ISSN:  1422-0067     ISO Abbreviation:  Int J Mol Sci     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101092791     Medline TA:  Int J Mol Sci     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  1006-17     Citation Subset:  -    
Affiliation:
Department of Chemistry and Biotechnology, Faculty of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama 240-8501, Japan; E-Mails: kawamoto-yukinori-tf@ynu.ac.jp (Y.K.); jojo@ynu.ac.jp (Y.O.); t-kaneko@ynu.ac.jp (T.K.); kkensei@ynu.ac.jp (K.K.).
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