Document Detail

Photoselective prostatic vaporization for bladder outlet obstruction: 12-month evaluation of storage and voiding symptoms.
MedLine Citation:
PMID:  20092849     Owner:  NLM     Status:  MEDLINE    
PURPOSE: We evaluated voiding and storage symptom evolution in patients treated with prostate photoselective vaporization by a KTP laser. MATERIALS AND METHODS: Enrolled in the study were 150 consecutive patients with lower urinary tract symptoms due to benign prostatic hyperplasia and a diagnosis of bladder outlet obstruction. Patients underwent prostate photoselective vaporization with the 80 W KTP laser. Baseline parameters included prostate volume, International Prostate Symptom Score with voiding and storage symptom subscores, uroflowmetry, pressure flow study and serum prostate specific antigen. Patients were followed 1, 3, 6 and 12 months after surgery. RESULTS: Mean +/- SD patient age was 69.6 +/- 10 years. Mean prostate volume was 52 +/- 18 ml. Mean International Prostate Symptom Score was 22.3 +/- 4, mean maximum urine flow was 9 +/- 2.9 ml per second and mean Sch?fer obstruction class was 3.6 +/- 1. An average of 190 +/- 44 kJ were delivered in a mean of 68 +/- 24 minutes with an average of 3.6 kJ/ml prostate. The mean number of fibers was 1.2 +/- 0.4. Mean catheterization time was 20 +/- 8 hours. Retrograde ejaculation was reported in 67% of patients. Prostate specific antigen was significantly decreased at 12 months (2.6 +/- 2.3 vs 0.9 +/- 0.7 ng/ml, p = 0.001). Storage symptoms decreased by 54.5%, 63.6%, 72.7% and 81.8% at 1, 3, 6 and 12 months, respectively (p <0.001). Voiding symptoms decreased 63.6%, 72.7%, 81.8% and 90.9% at 1, 3, 6 and 12 months, respectively (p <0.001). CONCLUSIONS: As shown by a prostate specific antigen significant decrease, proper prostate debulking may be achieved by prostate photoselective vaporization. Significant continuous improvement in storage and voiding symptoms was observed at up to 12-month followup.
Cosimo De Nunzio; Roberto Miano; Alberto Trucchi; Lucio Miano; Giorgio Franco; Stefano Squillacciotti; Andrea Tubaro
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Publication Detail:
Type:  Journal Article     Date:  2010-01-21
Journal Detail:
Title:  The Journal of urology     Volume:  183     ISSN:  1527-3792     ISO Abbreviation:  J. Urol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-17     Completed Date:  2010-03-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1098-103     Citation Subset:  AIM; IM    
Copyright Information:
2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.
Department of Urology, Sant'Andrea Hospital, University La Sapienza, Rome, Italy.
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MeSH Terms
Aged, 80 and over
Middle Aged
Prostatic Hyperplasia / complications*,  surgery*
Time Factors
Transurethral Resection of Prostate*
Urinary Bladder Neck Obstruction / etiology*,  surgery*
Comment In:
J Urol. 2010 Mar;183(3):1103-4   [PMID:  20092839 ]

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