Document Detail

Photokymography: a noninvasive method of detecting ischemic segmental myocardial wall motion abnormalities.
MedLine Citation:
PMID:  425916     Owner:  NLM     Status:  MEDLINE    
The photokymograph is a new and simple noninvasive device for assessing epicardial segmental myocardial wall motion utilizing cardiac fluoroscopy and image intensification. The validity of this technique in detecting wall motion changes occurring with ischemia was assessed in seven closed chest dogs undergoing acute balloon occlusion of the left circumflex coronary artery. Acute occlusion resulted in a prompt change in the analog signal of the photokymogram, characterized first by a decreased systolic inward motion and late systolic outward movement that later became akinetic and dyskinetic. Systolic amplitude decreased 18 +/- 7 percent (mean +/- standard error of the mean) within 5 seconds of occlusion and progressed to systolic outward motion (- 106 +/- 24 percent) at 2 minutes. The time course and type of morphologic changes observed after occlusion were similar to those previously described using invasive methods. Furthermore, such changes preceded electrocardiographic S-T segment elevation. These data suggest that photokymography is a sensitive technique for noninvasive detection of acute ischemic segmental wall motion abnormalities and holds promise as a simple method of detecting ischemic heart disease in man.
M Pichler; G A Diamond; M Hirsch; R Vas; D Tzivoni; H J Swan; J S Forrester
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  43     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1979 Apr 
Date Detail:
Created Date:  1979-05-26     Completed Date:  1979-05-26     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  794-800     Citation Subset:  AIM; IM    
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MeSH Terms
Arterial Occlusive Diseases / etiology
Coronary Disease / diagnosis*
Coronary Vessels / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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