Document Detail

Photodynamic therapy in dermatology: past, present, and future.
MedLine Citation:
PMID:  23149885     Owner:  NLM     Status:  Publisher    
ABSTRACT. Photodynamic therapy (PDT) is a noninvasive therapeutic method first introduced in the field of dermatology. It is mainly used for the treatment of precancerous and superficial malignant skin tumors. Today PDT finds new applications not only for nononcologic dermatoses but also in the field of other medical specialties such as otorhinolaryngology, ophthalmology, neurology, gastroenterology, and urology. We are witnessing a broadening of the spectrum of skin diseases that are treated by PDT. Since its introduction, PDT protocol has evolved significantly in terms of increasing method efficacy and patient safety. In this era of evidence-based medicine, it is expected that much effort will be put into creating a worldwide accepted consensus on PDT. A review on the current knowledge of PDT is given, and the historical basis of the method's evolution since its introduction in the 1900s is presented. At the end, future challenges of PDT are focused on discussing gaps that exist for research in the field.
Razvigor Darlenski; Joachim W Fluhr
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Publication Detail:
Journal Detail:
Title:  Journal of biomedical optics     Volume:  18     ISSN:  1560-2281     ISO Abbreviation:  J Biomed Opt     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2012-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9605853     Medline TA:  J Biomed Opt     Country:  -    
Other Details:
Languages:  ENG     Pagination:  61208     Citation Subset:  -    
Tokuda Hospital-Sofia, Department of Dermatology and Venereology, 51 B Nikola Vaptsarov Building, 1407 Sofia, Bulgaria.
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