Document Detail

Photodegradation and inhibition of drug-resistant influenza virus neuraminidase using anthraquinone-sialic acid hybrids.
MedLine Citation:
PMID:  23282898     Owner:  NLM     Status:  Publisher    
The anthraquinone-sialic acid hybrids designed effectively degraded not only non-drug-resistant neuraminidase but also drug-resistant neuraminidase, which is an important target of anti-influenza therapy. Degradation was achieved using long-wavelength UV radiation in the absence of any additives and under neutral conditions. Moreover, the hybrids efficiently inhibited neuraminidase activities upon photo-irradiation.
Yusuke Aoki; Shuho Tanimoto; Daisuke Takahashi; Kazunobu Toshima
Related Documents :
23827778 - Radioprotective role of clinical drug diclofenac sodium.
22172168 - Virtual design of chemical penetration enhancers for transdermal drug delivery.
11346898 - A review of the isolated kidney as an experimental model for pharmacokinetic studies.
17803728 - Allometric scaling of marbofloxacin, moxifloxacin, danofloxacin and difloxacin pharmaco...
23482318 - Sustained release enteric coated tablets of pantoprazole: formulation, in vitro and in ...
15561458 - Tobacco-reporting validity in an epidemiological drug-use survey.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-3
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an ...
Next Document:  Differential role of hypoxia-inducible factor 1 alpha in toll-like receptor-mediated and allergic in...