Document Detail


Photodeactivation of ethyl violet: a potential hazard of Sodasorb.
MedLine Citation:
PMID:  2105069     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Breathing circuit cannisters containing functional CO2 absorbent are critical to prevent rebreathing CO2 during general anesthesia using closed or semiclosed breathing systems. Ethyl violet is the indicator dye added to Sodasorb to indicate impending exhaustion of the absorbent. A case of CO2 rebreathing due to failure of ethyl violet indicator in exhausted Sodasorb was encountered. Laboratory investigation demonstrated that dye failure could result from photodeactivation caused by fluorescent lights. Using a fixed intensity fluorescent light source and quantitative spectrophotometric analysis, a highly significant dose-response relationship was demonstrated between duration of light exposure and the decrease in ethyl violet concentration. After 24 h of fluorescent light exposure with a received flux density of 46 nwatts/cm2 at 254 nm, the concentration of functional ethyl violet remaining in pulverized Sodasorb was 16% of the baseline value. Furthermore, using multiple light sources of various intensities, the greater the intensity of light, the more rapid the rate of decline of the ethyl violet concentration. It is recommended to minimize the problem by using ultraviolet filters and incorporating additional ethyl violet in Sodasorb. Finally, ethyl violet undergoes temporal deactivation after a Sodasorb container is opened, even if it is stored in the dark.
Authors:
J J Andrews; R V Johnston; D E Bee; J F Arens
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anesthesiology     Volume:  72     ISSN:  0003-3022     ISO Abbreviation:  Anesthesiology     Publication Date:  1990 Jan 
Date Detail:
Created Date:  1990-02-21     Completed Date:  1990-02-21     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  1300217     Medline TA:  Anesthesiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  59-64     Citation Subset:  AIM; IM    
Affiliation:
Department of Anesthesia, University of Texas Medical Branch, Galveston 77550-2778.
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MeSH Terms
Descriptor/Qualifier:
Absorption
Anesthesia, Closed-Circuit / instrumentation*
Anesthesia, Inhalation / instrumentation*
Carbon Dioxide*
Coloring Agents
Humans
Indicators and Reagents
Light
Rosaniline Dyes*
Chemical
Reg. No./Substance:
0/Coloring Agents; 0/Indicators and Reagents; 0/Rosaniline Dyes; 124-38-9/Carbon Dioxide; 47743-68-0/ethyl violet

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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