Document Detail


Photocoagulation treatment of proliferative diabetic retinopathy. Clinical application of Diabetic Retinopathy Study (DRS) findings, DRS Report Number 8. The Diabetic Retinopathy Study Research Group.
MedLine Citation:
PMID:  7196564     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Additional follow-up confirms previous reports from the Diabetic Retinopathy Study (DRS) that photocoagulation, as used in the study, reduces the risk of severe visual loss by 50% or more. Decreases of visual acuity of one or more lines and constriction of peripheral visual field due to treatment were also observed in some eyes. These harmful effects were more frequent and more severe following the DRS xenon technique. The two-year risk of severe visual loss without treatment outweighs the risk of harmful treatment effects for two groups of eyes: (1) eyes with new vessels and preretinal or vitreous hemorrhage; and (2) eyes with new vessels on or within one disc diameter of the optic disc (NVD) equaling or exceeding 1/4 to 1/3 disc area in extent, (Fig 1), even in the absence of preretinal or vitreous hemorrhage. For eyes with these characteristics, prompt treatment is usually advisable. For eyes with less severe retinopathy, DRS findings do not provide a clear choice between prompt treatment or deferral unless progression to these more severe stages occurs.
Authors:
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Ophthalmology     Volume:  88     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-10-29     Completed Date:  1981-10-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  583-600     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Argon
Child
Child, Preschool
Diabetic Retinopathy / surgery*
Female
Follow-Up Studies
Fundus Oculi
Humans
Laser Therapy*
Lasers / adverse effects,  methods*
Male
Middle Aged
Visual Acuity
Visual Fields
Xenon
Chemical
Reg. No./Substance:
7440-37-1/Argon; 7440-63-3/Xenon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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