Document Detail

Photochromically-controlled, reversibly-activated MRI and optical contrast agent.
MedLine Citation:
PMID:  17377672     Owner:  NLM     Status:  MEDLINE    
The contrast agent which tethers a spiropyran group to a Gd-DO3A moiety has higher relaxivity and fluorescence intensity in the dark; the relaxivity and fluorescence intensity decrease after irradiation with visible light.
Chuqiao Tu; Angelique Y Louie
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2007-01-18
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1359-7345     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-22     Completed Date:  2007-05-23     Revised Date:  2014-09-21    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  1331-3     Citation Subset:  IM    
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MeSH Terms
Contrast Media / chemical synthesis,  chemistry*
Magnetic Resonance Imaging
Molecular Structure
Grant Support
R03 EY013941/EY/NEI NIH HHS; R03 EY013941-01/EY/NEI NIH HHS; R03 EY13941-01/EY/NEI NIH HHS
Reg. No./Substance:
0/Contrast Media

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