Document Detail

Photochromic nucleobase: reversible photoisomerization, photochemical properties and photoregulation of hybridization.
MedLine Citation:
PMID:  18776407     Owner:  NLM     Status:  In-Process    
We have developed a set of photochromic nucleobases (PCNs), which reversibly change the photochemical and physical properties such as fluorescence intensity upon cis-trans photoisomerization by the external light stimuli. PCNs showed very rapid and efficient reversible photoisomerization by illumination at specific wavelength. In addition, photoisomerization can be iteratively performed by alternate illumination with 250 approximately 350 nm and 350 approximately 500 nm light without any side reactions. We demonstrated a new type of the photoregulation of hybridization using this switching property.
Shinzi Ogasawara; Mizuo Maeda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nucleic acids symposium series (2004)     Volume:  -     ISSN:  1746-8272     ISO Abbreviation:  Nucleic Acids Symp Ser (Oxf)     Publication Date:  2008  
Date Detail:
Created Date:  2008-09-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101259965     Medline TA:  Nucleic Acids Symp Ser (Oxf)     Country:  England    
Other Details:
Languages:  eng     Pagination:  369-70     Citation Subset:  IM    
Bioengineering Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
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