Document Detail


Photochemistry of pyrimidine bases as studied by e.s.r. and spin-trapping.
MedLine Citation:
PMID:  6271695     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The direct photoexcitation of pyrimidine bases in D2O solutions yields free radicals which could be conveniently identified by spin-trapping with 2-methyl-2-nitrosopropane. Most of the radicals formed were attributed to D-addition to one end of the 5,6 double bond. However, orotic acid and iso-orotic acid yielded N(3) centred free radicals, formed by homolytic cleavage of the N-H bond. No indication could be found for a free radical involvement in the photocleavage of cyclobutane-type pyrimidine dimers.
Authors:
I Rosenthal; M M Mossoba; P Riesz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of radiation biology and related studies in physics, chemistry, and medicine     Volume:  40     ISSN:  0020-7616     ISO Abbreviation:  Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med.     Publication Date:  1981 Oct 
Date Detail:
Created Date:  1982-01-09     Completed Date:  1982-01-09     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0374725     Medline TA:  Int J Radiat Biol Relat Stud Phys Chem Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  385-95     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Electron Spin Resonance Spectroscopy / methods
Free Radicals
Photochemistry
Pyrimidines*
Chemical
Reg. No./Substance:
0/Free Radicals; 0/Pyrimidines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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