Document Detail


Photocatalytic inactivation of bacteriophages by TiO(2)-coated glass plates under low-intensity, long-wavelength UV irradiation.
MedLine Citation:
PMID:  21931933     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The International Organization for Standardization (ISO) was used to evaluate antibacterial activity by titanium dioxide (TiO(2)) photocatalysis since 2006. We evaluated photocatalytic inactivation of Qβ and T4 bacteriophages induced by low-intensity, long-wavelength ultraviolet A (UVA; 0.1 mW cm(-2) and 0.001 mW cm(-2)) irradiation on a TiO(2)-coated glass plate using the ISO methodology. The results indicated that both bacteriophages were inactivated at 0.001 mW cm(-2) UVA. The intensity of UV light, including long-wavelength light (UVA), is very low in an actual indoor environment. Thus, TiO(2) photocatalysis can be beneficial for inactivating viruses in an indoor environment. Experiments using qPCR and bovine serum albumin degradation assume that viral inactivation is caused by outer viral protein disorder and not by viral RNA reduction by reactive oxygen species produced during TiO(2) photocatalysis. Furthermore, we showed that the ISO methodology for standard testing of antibacterial activity by TiO(2) photocatalysis can be applied to assess antiviral activity.
Authors:
Hitoshi Ishiguro; Ryuichi Nakano; Yanyan Yao; Jitsuo Kajioka; Akira Fujishima; Kayano Sunada; Masafumi Minoshima; Kazuhito Hashimoto; Yoshinobu Kubota
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-20
Journal Detail:
Title:  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology     Volume:  -     ISSN:  1474-9092     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101124451     Medline TA:  Photochem Photobiol Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Photocatalyst Group, Kanagawa Academy of Science and Technology, KSP West Building, 614, 3-2-1, Sakado, Takatsu-ku, Kawasaki, Kanagawa 213-0012, Japan.
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