Document Detail

Photoallergic contact dermatitis to musk ambrette. Clinical report of two patients with persistent light reactor patterns.
MedLine Citation:
PMID:  7430459     Owner:  NLM     Status:  MEDLINE    
Two male patients with photoallergic contact dermatitis to musk ambrette, 2-methoxy-3,5-dinitro-4-methyl-t-butylbenzene, are reported. Musk ambrette is a synthetic fragrance material commonly used in foods and cosmetics. The clinical distribution of lesions presented by these patients strongly suggested an adverse reaction to light. Over a period of several years no etiology had been determined in these cases despite extensive testing and hospitalization. Photopatch tests to musk ambrette were positive. No other etiology for photosensitivity was found. This report emphasizes that exposure to household or cosmetic products represents a potential source of contact photosensitivity. Patients presenting with dermatoses of unknown origin confined to the light-exposed areas should have fragrances considered as possible etiologic agents.
V J Giovinazzo; L C Harber; R B Armstrong; I E Kochevar
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  3     ISSN:  0190-9622     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  1980 Oct 
Date Detail:
Created Date:  1981-01-26     Completed Date:  1981-01-26     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  384-93     Citation Subset:  IM    
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MeSH Terms
Cosmetics / adverse effects
Dermatitis, Contact / diagnosis,  etiology*,  pathology
Dinitrobenzenes / adverse effects*
Nitrobenzenes / adverse effects*
Patch Tests
Perfume / adverse effects*
Photosensitivity Disorders / chemically induced*,  diagnosis,  pathology
Skin / pathology
Grant Support
Reg. No./Substance:
0/Cosmetics; 0/Dinitrobenzenes; 0/Nitrobenzenes; 0/Perfume; 83-66-9/musk ambrette (artificial)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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