Document Detail


Photoacoustic imaging: a potential tool to detect early indicators of metastasis.
MedLine Citation:
PMID:  23278229     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The metastasis of cancer is a multistage process involving complex biological interactions and difficult to predict outcomes. Accurate assessment of the extent of metastasis is critical for clinical practice; unfortunately, medical imaging methods capable of identifying the early stages of invasion and metastasis are lacking. Photoacoustic imaging is capable of providing noninvasive, real-time imaging of significant anatomical and physiological changes. indicating the progression of cancer invasion and metastasis. Preclinically, photoacoustic methods have been used to image lymphatic anatomy, including the sentinel lymph nodes, to identify circulating tumor cells within vasculature and to detect micrometastases. Progress has begun toward the development of clinically applicable photoacoustic imaging systems to assist with the determination of cancer stage and likelihood of metastatic invasion.
Authors:
Carolyn L Bayer; Pratixa P Joshi; Stanislav Y Emelianov
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Expert review of medical devices     Volume:  10     ISSN:  1745-2422     ISO Abbreviation:  Expert Rev Med Devices     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-02     Completed Date:  2013-05-30     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  101230445     Medline TA:  Expert Rev Med Devices     Country:  England    
Other Details:
Languages:  eng     Pagination:  125-34     Citation Subset:  IM    
Affiliation:
Department of Biomedical Engineering, The University of Texas at Austin, 1 University Station, Austin, TX 78712, USA. carolynbayer@austin.utexas.edu
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MeSH Terms
Descriptor/Qualifier:
Diagnostic Imaging / instrumentation,  methods*,  trends*
Humans
Neoplasm Metastasis / diagnosis*
Photoacoustic Techniques / instrumentation,  methods*,  trends*
Grant Support
ID/Acronym/Agency:
CA159913/CA/NCI NIH HHS; EB008101/EB/NIBIB NIH HHS; F32 CA159913/CA/NCI NIH HHS; R01 CA149740/CA/NCI NIH HHS; R01 EB008101/EB/NIBIB NIH HHS
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