Document Detail

Phosphorylation of Histone H3S10 in Animal Chromosomes: Is There a Uniform Pattern?
MedLine Citation:
PMID:  21893968     Owner:  NLM     Status:  Publisher    
Phosphorylation of serine 10 in histone H3 (H3S10ph) has been extensively analyzed and appears to be a conserved chromatin change associated with chromosome condensation in different eukaryotic organisms. In this work, we report the distribution of H3S10ph during meiosis in monocentric and holokinetic chromosomes of 6 insect species and in mitotic chromosomes of 7 mammalian species, aiming to investigate the labeling patterns in phylogenetically distant groups. The results indicated a very similar phosphorylation timing and distribution pattern among insects. The sex chromosomes of insects analyzed were always undercondensed and hypophosphorylated. Similarly, the micro chromosomes of the bug Pachylis aff pharaonis were also undercondensed and hypophosphorylated. Holokinetic chromosomes of bugs and monocentric chromosomes of grasshoppers and beetles displayed identical phosphorylation pattern in spite of the difference in the centromere type. Among mammals, a uniform chromosome phosphorylation was observed in marsupials, whereas bat chromosomes displayed a longitudinal banding pattern. These data indicate that, in general, the intensity of H3S10 phosphorylation in animal chromosomes is variable among the distinct chromosome types and associated with the degree of chromatin condensation at metaphase, but it may vary between different groups of animals.
C G Sotero-Caio; M J de Souza; D C Cabral-de-Mello; A C Brasileiro-Vidal; M Guerra
Related Documents :
7991418 - Correlation of the endocardial fragmented electrogram with body surface signal-averaged...
15838558 - Molecular mapping of the chlorophyll retainer (cl) mutation in pepper (capsicum spp.) a...
22285018 - A t(1;9)(q10;q10) translocation with additional 6q23 and 9q22 rearrangements in a case ...
293128 - A maximum likelihood map of chromosome 1.
14511298 - Exclusion of mosaicism in spanish haemophilia a families with inversion of intron 22.
1424988 - Chromosome ends in chironomus pallidivittatus contain different subfamilies of telomere...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-30
Journal Detail:
Title:  Cytogenetic and genome research     Volume:  -     ISSN:  1424-859X     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-9-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101142708     Medline TA:  Cytogenet Genome Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 S. Karger AG, Basel.
Departamento de Genética, Centro de Ciências Biológicas, Universidade Federal de Pernambuco, Recife, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of Down s...
Next Document:  Hypospadias in a Male (78,XY; SRY-positive) Dog and Sex Reversal Female (78,XX; SRY-negative) Dogs: ...