| Phosphorus liver MRSI at 3 T using a novel dual-tuned eight-channel (31) P/(1) H coil. | |
| | |
MedLine Citation:
|
PMID: 22287206 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Although phosphorus-31 ((31) P) magnetic resonance spectroscopy holds potential as noninvasive tool to monitor treatment response of liver malignancies, the lack of appropriate coils has so far restricted its use to liver lesions close to the surface. A novel eight-channel phased-array dual-tuned (31) P/(1) H coil that can assess (31) P metabolism in deeper liver tissue as well is presented in this article. Analysis of its performance demonstrates that this coil can provide good sensitivity across a width of 20 cm, thereby enabling magnetic resonance spectroscopic imaging (MRSI) scans that can fully cover axial views of the abdomen in lean subjects. In vivo results and reproducibility of (31) P MRSI at 3 T of axial slices covering the full depth of the liver are shown in healthy volunteers. To minimize intrasubject and intersubject data variability, spectra are corrected for coil sensitivities. Methods to maximize the reproducibility of coil placement and spectroscopic planning are discussed. The phosphomonoesters/phosphodiesters ratio calculated in healthy volunteers has an average intrasubject variation of 23% averaged over voxels selected from the entire liver. Finally, the feasibility of using the coil in the clinic is shown by preliminary (31) P liver MRSI data obtained from a patient with hepatocellular carcinoma. Magn Reson Med, 2012. © 2012 Wiley Periodicals, Inc. |
| | |
Authors:
|
Anshuman Panda; Scott Jones; Helmut Stark; Rahul S Raghavan; Kumar Sandrasegaran; Navin Bansal; Ulrike Dydak |
Related Documents
:
|
18429016 - Automatic passive tracking of an endorectal prostate biopsy device using phase-only cro... 15078906 - Magnetic anchor for more effective endoscopic mucosal resection. 9057526 - Biopsy of hepatic dome lesions: semi-real-time coronal mr guidance technique. 22577046 - A comparison of hepatic segmental anatomy as revealed by cross-sections and mpr ct imag... 21688066 - Main pulmonary artery diameter from attenuation correction ct scans in cardiac spect ac... 3132826 - Mr evaluation of neurovascular lesions after endovascular occlusion with detachable bal... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-27 |
Journal Detail:
|
Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: - ISSN: 1522-2594 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-30 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 Wiley Periodicals, Inc. |
Affiliation:
|
School of Health Sciences, Purdue University, West Lafayette, Indiana, USA; Departmemt of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Targeting the enhancer of zeste homologue 2 in medulloblastoma.
Next Document: Similarity and number of alternatives in the random-dot motion paradigm.