Document Detail


Phosphoramidites: privileged ligands in asymmetric catalysis.
MedLine Citation:
PMID:  20333685     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Asymmetric catalysis with transition-metal complexes is the basis for a vast array of stereoselective transformations and has changed the face of modern synthetic chemistry. Key to this success has been the design of chiral ligands to control the regio-, diastereo-, and enantioselectivity. Phosphoramidites have emerged as a highly versatile and readily accessible class of chiral ligands. Their modular structure enables the formation of ligand libraries and easy fine-tuning for a specific catalytic reaction. Phosphoramidites frequently show exceptional levels of stereocontrol, and their monodentate nature is essential in combinatorial catalysis, where a ligand-mixture approach is used. In this Review, recent developments in asymmetric catalysis with phosphoramidites used as ligands are discussed, with a focus on the formation of carbon-carbon and carbon-heteroatom bonds.
Authors:
Johannes F Teichert; Ben L Feringa
Related Documents :
19724785 - Copper-catalyzed enantioselective carbenoid insertion into s-h bonds.
15069185 - Enantioselective diels-alder reactions catalyzed by hydrogen bonding.
12895055 - Chiral binaphthylthiophosphoramide-cu(i)-catalyzed asymmetric addition of diethylzinc t...
17221995 - Spontaneous enzymatically mediated dynamic kinetic resolution of 8-amino-5,6,7,8-tetrah...
12377035 - Nitric oxide photorelease from ruthenium salen complexes in aqueous and organic solutions.
17305335 - Tetrahedral d atom coordination of nickel and evidence for anti-isostructural phase tra...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Angewandte Chemie (International ed. in English)     Volume:  49     ISSN:  1521-3773     ISO Abbreviation:  Angew. Chem. Int. Ed. Engl.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-29     Completed Date:  2010-06-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370543     Medline TA:  Angew Chem Int Ed Engl     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  2486-528     Citation Subset:  -    
Affiliation:
Stratingh Institute for Chemistry and Center for Systems Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial ...
Next Document:  Liposome Destabilization by a 2,7-Diazapyrenium Derivative Through Formation of Transient Pores in t...