Document Detail


Phospholipid substrate-specificity of the L-serine base-exchange enzyme in rat liver microsomal fraction.
MedLine Citation:
PMID:  6430274     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The specificity of the L-serine base-exchange enzyme towards the fatty acid composition of the phospholipid substrate was investigated with a rat liver microsomal fraction. The relative rates of L-serine incorporation into saturated-hexaenoic, saturated-pentaenoic, saturated-tetraenoic, saturated-trienoic, dienoic-dienoic, monoenoic-dienoic, saturated-dienoic and saturated-monoenoic + saturated-saturated phosphatidylserine molecular species were 42, 5, 23, 4, 5, 4, 5 and 11% respectively. This is similar to, but not identical with, the relative mass abundance of these molecular species in total liver cell phosphatidylserines. The results indicate that the substrate-specificity of the L-serine base-exchange enzyme can at least in part explain the observed fatty acid composition of rat liver phosphatidylserines.
Authors:
K S Bjerve
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  The Biochemical journal     Volume:  219     ISSN:  0264-6021     ISO Abbreviation:  Biochem. J.     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-08-08     Completed Date:  1984-08-08     Revised Date:  2010-09-13    
Medline Journal Info:
Nlm Unique ID:  2984726R     Medline TA:  Biochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  781-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Female
Microsomes, Liver / enzymology,  metabolism*
Nitrogenous Group Transferases*
Phosphatidylserines / biosynthesis*
Phospholipids / metabolism*
Rats
Rats, Inbred Strains
Serine / metabolism
Substrate Specificity
Transferases / metabolism*
Chemical
Reg. No./Substance:
0/Phosphatidylserines; 0/Phospholipids; 56-45-1/Serine; EC 2.-/Transferases; EC 2.6.-/Nitrogenous Group Transferases; EC 2.7.8.-/phospholipid serine base exchange enzyme
Comments/Corrections

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