Document Detail

Phospholipases of Candida albicans.
MedLine Citation:
PMID:  11766099     Owner:  NLM     Status:  MEDLINE    
Infections due to Candida albicans are frequent and of clinical importance. Especially at a time of increasing organ transplantations, HIV infections, and resistance to antimicrobial agents a profound knowledge of the interaction between C. albicans and host tissue is mandatory. In addition to secreted aspartyl proteinase, dimorphism, cell surface composition, and toxin production phospholipases are a main factor in pathogenicity. Up to the present, many different groups and subgroups of phospholipases have been detected. These different enzymes are related to various types of aggressive and defensive actions. These range from active invasion of host cell tissue to growth control and remodelling of the yeast cell membrane. It is clear that a multiplicity of factors must co-operate to overcome the host's defences. Yet it can be supposed today that phospholipases are one important factor in this complex interaction. Therefore the known phospholipases of C. albicans are described in detail under clinical aspects.
M Niewerth; H C Korting
Related Documents :
20624999 - Plant immunity directly or indirectly restricts the injection of type iii effectors by ...
2192699 - Tumour necrosis factor in surgical illness.
2406869 - Animal model system for studying virulence of and host response to bacteroides fragilis.
8665089 - Battling against host phagocytes: the wherefore of the rtx family of toxins?
21432289 - Mechanism of cytotoxicity of paraquat.
16356719 - Francisella tularensis travels a novel, twisted road within macrophages.
14973069 - Resveratrol inhibits drug-induced apoptosis in human leukemia cells by creating an intr...
17936359 - Calreticulin requires an ancillary adjuvant for the induction of efficient cytotoxic t ...
24127169 - Apoptosis in larval and frog skin of rana pipiens, r. catesbeiana, and ceratophrys ornata.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Mycoses     Volume:  44     ISSN:  0933-7407     ISO Abbreviation:  Mycoses     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-12-18     Completed Date:  2002-02-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8805008     Medline TA:  Mycoses     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  361-7     Citation Subset:  IM    
Klinikum der Universität München, Klinik und Poliklinik für Dermatologie und Allergologie, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Candida albicans / enzymology*,  pathogenicity
Candidiasis / microbiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Aspergillus detection in bronchoscopically acquired material. Significance and interpretation.
Next Document:  Extrusion of fluorescein diacetate by multidrug-resistant Candida albicans.