Document Detail


Phospholipase D-catalyzed synthesis of novel phospholipid-phytosterol conjugates.
MedLine Citation:
PMID:  15638246     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the present study, plant sterols were modified to form amphiphiles by synthesizing phospholipid derivatives from them so they could be formulated in different functional foods and possibly improve their effects as therapeutic agents. The new phosphatidyl derivatives, phosphatidyl-sitosterols, were synthesized by the transfer reaction of a phosphatidyl residue from PC to beta-sitosterol by phospholipase D (PLD EC 3.1.4.4) from Streptomyces sp. in a biphasic medium.
Authors:
Monjur Hossen; Ernesto Hernandez
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Lipids     Volume:  39     ISSN:  0024-4201     ISO Abbreviation:  Lipids     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2005-01-10     Completed Date:  2005-05-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0060450     Medline TA:  Lipids     Country:  United States    
Other Details:
Languages:  eng     Pagination:  777-82     Citation Subset:  IM    
Affiliation:
Food Protein R&D Center, Texas A&M University, College Station, Texas 77843-2476, USA.
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MeSH Terms
Descriptor/Qualifier:
Catalysis
Chromatography, Thin Layer
Molecular Structure
Phospholipase D / metabolism*
Phospholipids / biosynthesis,  chemistry,  metabolism*
Phytosterols / biosynthesis,  chemistry,  metabolism*
Soybeans / chemistry,  metabolism
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Streptomyces / enzymology
Chemical
Reg. No./Substance:
0/Phospholipids; 0/Phytosterols; EC 3.1.4.4/Phospholipase D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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