| Phosphaturic mesenchymal tumor, mixed connective tissue variant, of the mandible: report of a case and review of the literature. | |
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MedLine Citation:
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PMID: 19828339 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome that results in renal phosphate wasting with hypophosphatemia. In most cases, the underlying cause of TIO is a small mesenchymal neoplasm that is often difficult to detect, resulting in delayed diagnosis. One such neoplasm is the phosphaturic mesenchymal tumor, mixed connective tissue variant (PMTMCT), an unusual entity with unique morphologic and biochemical features. Most of these tumors are found at appendicular sites with only rare cases reported in the jaws. We describe a PMTMCT involving the mandible in a patient with a protracted history of osteomalacia. A review of the current literature is provided with emphasis on the clinical and histologic features, etiopathogenesis, and management of PMTMCT in the setting of TIO. |
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Authors:
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Victoria L Woo; Regina Landesberg; Erik A Imel; Steven R Singer; Andrew L Folpe; Michael J Econs; Taeyun Kim; Lara R Harik; Thomas P Jacobs |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Review Date: 2009-10-14 |
Journal Detail:
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Title: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics Volume: 108 ISSN: 1528-395X ISO Abbreviation: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-11-16 Completed Date: 2010-03-05 Revised Date: 2011-05-05 |
Medline Journal Info:
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Nlm Unique ID: 9508562 Medline TA: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Country: United States |
Other Details:
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Languages: eng Pagination: 925-32 Citation Subset: D; IM |
Affiliation:
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Department of Biomedical Sciences, School of Dental Medicine, University of Nevada, Las Vegas, NV 89106, USA. victoria.woo@unlv.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Hypophosphatemia / etiology, pathology, therapy Mandibular Neoplasms / complications*, pathology, surgery Mesenchymoma / complications*, pathology, surgery Neoplasms, Connective Tissue / complications*, pathology, surgery Osteomalacia / etiology*, pathology, therapy Paraneoplastic Syndromes / complications, pathology*, therapy |
| Grant Support | |
ID/Acronym/Agency:
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DK32333/DK/NIDDK NIH HHS; KL2RR025760-01/RR/NCRR NIH HHS; R01 AR042228-15/AR/NIAMS NIH HHS; R01 AR042228-17/AR/NIAMS NIH HHS; R01 AR42228/AR/NIAMS NIH HHS; R01 DK032333-24A2/DK/NIDDK NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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