Document Detail


Phosphatidylserine delivery to endoplasmic reticulum-derived vesicles of plant cells depends on two biosynthetic pathways.
MedLine Citation:
PMID:  11389893     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Vesicles formed from endoplasmic reticulum (ER) by a cell-free system of leek cells (Allium porrum) are enriched in phosphatidylserine (PS), especially species containing very long chain fatty acids (VLCFA, at least 20 carbon atoms). In plant cells, PS is formed either by PS synthase or the serine exchange enzyme, although it is not known which pathway(s) contribute(s) to PS delivery in the ER-derived vesicles (EV), nor to what extent this occurs. Taking advantage of a cell-free system, we have shown that PS enrichment originates mainly from the serine exchange enzyme which is the only pathway that synthesizes the VLCFA-PS species. On the other hand, both enzymes synthesize PS with long chain fatty acids (up to 18 carbon atoms), but these species are given to the EV by PS synthase.
Authors:
P Vincent; L Maneta-Peyret; C Cassagne; P Moreau
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  FEBS letters     Volume:  498     ISSN:  0014-5793     ISO Abbreviation:  FEBS Lett.     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-06-06     Completed Date:  2001-06-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0155157     Medline TA:  FEBS Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  32-6     Citation Subset:  IM    
Affiliation:
Laboratoire de Biogenèse Membranaire UMR 5544 CNRS, Université Victor Segalen Bordeaux 2, France. pmoreau@biomemb.u-bordeaux2.fr
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MeSH Terms
Descriptor/Qualifier:
Endoplasmic Reticulum / metabolism*
Onions / metabolism*
Phosphatidylinositols / biosynthesis
Phosphatidylserines / biosynthesis,  metabolism*
Chemical
Reg. No./Substance:
0/Phosphatidylinositols; 0/Phosphatidylserines

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