Document Detail

Phosphatidylglycerol and fetal lung maturity.
MedLine Citation:
PMID:  7114125     Owner:  NLM     Status:  MEDLINE    
The lecithin/sphingomyelin (L/S) ratio has been reported to be inadequate as a predictor of fetal surfactant maturity in many complicated obstetric cases, particularly in patients with diabetes. L/S ratios are also unreliable when the sample contains blood or meconium. Phosphatidylglycerol (PG) is present only in amniotic fluid and respiratory tract effluent. PG may characterize surfactant maturity in samples of amniotic fluid contaminated with blood or meconium as well as specimens collected from the vagina in cases of premature rupture of membranes. Three hundred eleven samples of amniotic fluid collected from January, 1980, to June, 1981, were analyzed for L/S ratio and PG. This report analyses the ability of these tests to predict neonatal maturity in normal and complicated obstetric cases.
W C Plauché; S Faro; R Letellier
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  144     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1982-10-29     Completed Date:  1982-10-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  167-72     Citation Subset:  AIM; IM    
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MeSH Terms
Amniotic Fluid / analysis
Fetal Organ Maturity
Lung / embryology*
Phosphatidylcholines / analysis
Phosphatidylglycerols / analysis*
Pregnancy Complications / metabolism
Sphingomyelins / analysis
Reg. No./Substance:
0/Phosphatidylcholines; 0/Phosphatidylglycerols; 0/Sphingomyelins

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