Document Detail

Phosphate removal by resin hemoperfusion efficacy and biocompatibility of a new exchange resin.
MedLine Citation:
PMID:  1457689     Owner:  NLM     Status:  MEDLINE    
A new coated anionic exchange resin for blood purification specifically designed to remove phosphates was experimentally employed in animals. 3 pigs, in which uremia had been surgically induced, underwent 6 extracorporeal hemoperfusion sessions (2 per pig) with a cartridge containing 100 gr of resin. The phosphate clearance proved satisfactory, values being 120 ml/min after 10' and around 80 ml/min after 2 hours. The biocompatibility of the resin and of the coating membrane was satisfactory. The negligible variation in pH and plasma bicarbonate during all sessions confirmed the low absorption by the tested resin of other blood anions competing with phosphate.
L Colì; S Faenza; M Spighi; L C Borgnino; G Feliciangeli; G Cianciolo; A Faenza; G Martinelli; R Giardino; S Stefoni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology     Volume:  20     ISSN:  1055-7172     ISO Abbreviation:  Biomater Artif Cells Immobilization Biotechnol     Publication Date:  1992  
Date Detail:
Created Date:  1993-01-14     Completed Date:  1993-01-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  9111988     Medline TA:  Biomater Artif Cells Immobilization Biotechnol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1153-63     Citation Subset:  IM    
Nephrology Department, S. Orsola Hospital, Bologna, Italy.
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MeSH Terms
Bicarbonates / blood
Biocompatible Materials*
Chlorides / blood
Hemoperfusion / methods*
Hydrogen-Ion Concentration
Lactates / blood
Phosphates / metabolism
Resins, Plant*
Reg. No./Substance:
0/Bicarbonates; 0/Biocompatible Materials; 0/Chlorides; 0/Lactates; 0/Phosphates; 0/Resins, Plant

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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