Document Detail

Phlebosclerosis of the colon with positive anti-centromere antibody.
MedLine Citation:
PMID:  10397079     Owner:  NLM     Status:  MEDLINE    
A 56-year-old woman with symptoms of chronic bowel disease presented a peculiar calcification of the mesenteric vein of the ascending to transverse colon on barium enema study. The resected colon was hard and black. Histo-pathologic examinations demonstrated fibrous change of the colon with a calcified and hyaline-deposited mesenteric vein. No cell infiltration was observed. These findings were compatible with phlebosclerosis and also with systemic sclerosis. Positive anti-centromere antibody and Raynaud's phenomenon, hallmarks of a variant systemic sclerosis, the CREST syndrome were observed. We therefore speculated that the pathogenesis of the phlebosclerosis of the colon is related to the CREST syndrome.
T Kitamura; M Kubo; T Nakanishi; H Fushimi; K Yoshikawa; N Taenaka; T Furukawa; T Tsujimura; M Kameyama
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  38     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  1999 May 
Date Detail:
Created Date:  1999-08-09     Completed Date:  1999-08-09     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  416-21     Citation Subset:  IM    
Department of Internal Medicine, Sumitomo Hospital, Osaka.
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MeSH Terms
Autoantibodies / analysis*
CREST Syndrome / immunology,  pathology,  radiography
Calcinosis / immunology,  pathology*,  radiography
Centromere / immunology*
Colon / blood supply*,  pathology,  radiography
Mesenteric Veins / pathology*,  radiography
Middle Aged
Vascular Diseases / immunology,  pathology*,  radiography
Reg. No./Substance:
Comment In:
Intern Med. 1999 May;38(5):381   [PMID:  10397071 ]

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