| Pheochromocytoma with pyrexia and marked inflammatory signs: a paraneoplastic syndrome with possible relation to interleukin-6 production. | |
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MedLine Citation:
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PMID: 1890158 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pheochromocytoma can cause several paraneoplastic syndromes. We report a patient with pheochromocytoma who exhibited pyrexia and marked inflammatory signs along with an elevated serum interleukin-6 (IL-6) level. All of these abnormalities disappeared and serum IL-6 became undetectable by removal of the tumor. In addition, immunohistochemical analysis revealed the presence of IL-6 in the tumor cells. It is suggested that pyrexia and the elevation of acute phase proteins can be a paraneoplastic syndrome with pheochromocytoma, and that the elaboration of IL-6 from pheochromocytoma may play an important role in the development of the syndrome. |
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Authors:
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S Fukumoto; T Matsumoto; S Harada; J Fujisaki; M Kawano; E Ogata |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of clinical endocrinology and metabolism Volume: 73 ISSN: 0021-972X ISO Abbreviation: J. Clin. Endocrinol. Metab. Publication Date: 1991 Oct |
Date Detail:
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Created Date: 1991-10-17 Completed Date: 1991-10-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375362 Medline TA: J Clin Endocrinol Metab Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 877-81 Citation Subset: AIM; IM |
Affiliation:
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Fourth Department of Internal Medicine, University of Tokyo School of Medicine, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Gland Neoplasms
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complications*,
metabolism,
pathology Female Fever / complications*, metabolism, pathology Humans Immunohistochemistry Interleukin-6 / metabolism*, physiology Middle Aged Paraneoplastic Syndromes / metabolism, pathology* Pheochromocytoma / complications*, metabolism, pathology |
| Chemical | |
Reg. No./Substance:
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0/Interleukin-6 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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